This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4bgi
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='4bgi' size='340' side='right'caption='[[4bgi]], [[Resolution|resolution]] 2.09Å' scene=''> | <StructureSection load='4bgi' size='340' side='right'caption='[[4bgi]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4bgi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[4bgi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BGI FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I4I:3-HYDROXY-N-[(2R,5R,6S,9S,10S,11R)-10-HYDROXY-5,11-DIMETHYL-3,7,12-TRIOXO-2-(PROPAN-2-YL)-9-(PYRIDIN-3-YLMETHYL)-1,4-DIOXA-8-AZACYCLODODECAN-6-YL]PYRIDINE-2-CARBOXAMIDE'>I4I</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I4I:3-HYDROXY-N-[(2R,5R,6S,9S,10S,11R)-10-HYDROXY-5,11-DIMETHYL-3,7,12-TRIOXO-2-(PROPAN-2-YL)-9-(PYRIDIN-3-YLMETHYL)-1,4-DIOXA-8-AZACYCLODODECAN-6-YL]PYRIDINE-2-CARBOXAMIDE'>I4I</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | + | ||
| - | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bgi OCA], [https://pdbe.org/4bgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bgi RCSB], [https://www.ebi.ac.uk/pdbsum/4bgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bgi ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bgi OCA], [https://pdbe.org/4bgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bgi RCSB], [https://www.ebi.ac.uk/pdbsum/4bgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bgi ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/INHA_MYCTU INHA_MYCTU] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 27: | Line 27: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Cole | + | [[Category: Cole ST]] |
| - | [[Category: Hartkoorn | + | [[Category: Hartkoorn RC]] |
| - | [[Category: Pojer | + | [[Category: Pojer F]] |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of InhA(S94A) mutant in complex with OH-141
| |||||||||||
