This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4bkp
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | {{STRUCTURE_4bkp| PDB=4bkp | SCENE= }} | ||
| - | ===Crystal structure of human GDP-L-fucose synthase with bound NADP=== | ||
| - | == | + | ==Crystal structure of human GDP-L-fucose synthase with bound NADP== |
| - | [[ | + | <StructureSection load='4bkp' size='340' side='right'caption='[[4bkp]], [[Resolution|resolution]] 2.70Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[4bkp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BKP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BKP FirstGlance]. <br> |
| - | [[4bkp]] is a 4 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bkp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bkp OCA], [https://pdbe.org/4bkp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bkp RCSB], [https://www.ebi.ac.uk/pdbsum/4bkp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bkp ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FCL_HUMAN FCL_HUMAN] Two step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Bradley A]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Kavanagh | + | [[Category: Kavanagh K]] |
| - | [[Category: Krojer | + | [[Category: Krojer T]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Raynor | + | [[Category: Raynor JW]] |
| - | [[Category: Rojkova | + | [[Category: Rojkova A]] |
| - | [[Category: Shafqat | + | [[Category: Shafqat N]] |
| - | [[Category: Vollmar | + | [[Category: Vollmar M]] |
| - | [[Category: Yue | + | [[Category: Yue WW]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
Current revision
Crystal structure of human GDP-L-fucose synthase with bound NADP
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Bradley A | Edwards A | Kavanagh K | Krojer T | Oppermann U | Raynor JW | Rojkova A | Shafqat N | Vollmar M | Yue WW | Von Delft F
