This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4bqh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:56, 20 December 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor==
==Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor==
-
<StructureSection load='4bqh' size='340' side='right' caption='[[4bqh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
+
<StructureSection load='4bqh' size='340' side='right'caption='[[4bqh]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4bqh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BQH FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4bqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BQH FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9VU:(3S)-3-[2-(1,3-BENZODIOXOL-5-YL)-2-OXIDANYLIDENE-ETHYL]-4-BROMANYL-5-METHYL-3-OXIDANYL-1H-INDOL-2-ONE'>9VU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/UDP-N-acetylglucosamine_diphosphorylase UDP-N-acetylglucosamine diphosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.23 2.7.7.23] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9VU:(3S)-3-[2-(1,3-BENZODIOXOL-5-YL)-2-OXIDANYLIDENE-ETHYL]-4-BROMANYL-5-METHYL-3-OXIDANYL-1H-INDOL-2-ONE'>9VU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqh OCA], [http://pdbe.org/4bqh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bqh RCSB], [http://www.ebi.ac.uk/pdbsum/4bqh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bqh ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bqh OCA], [https://pdbe.org/4bqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bqh RCSB], [https://www.ebi.ac.uk/pdbsum/4bqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bqh ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q386Q8_TRYB2 Q386Q8_TRYB2]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: UDP-N-acetylglucosamine diphosphorylase]]
+
[[Category: Large Structures]]
-
[[Category: Fang, W]]
+
[[Category: Trypanosoma brucei]]
-
[[Category: Raimi, O G]]
+
[[Category: Fang W]]
-
[[Category: VanAalten, D M.F]]
+
[[Category: Raimi OG]]
-
[[Category: Inhibitor]]
+
[[Category: VanAalten DMF]]
-
[[Category: Transferase]]
+

Current revision

Crystal structure of the uridine diphosphate N-acetylglucosamine pyrophosphorylase from Trypanosoma brucei in complex with inhibitor

PDB ID 4bqh

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bqh"
Personal tools