This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4bvt

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:59, 20 December 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==Cyanuric acid hydrolase: evolutionary innovation by structural concatenation==
==Cyanuric acid hydrolase: evolutionary innovation by structural concatenation==
-
<StructureSection load='4bvt' size='340' side='right' caption='[[4bvt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
+
<StructureSection load='4bvt' size='340' side='right'caption='[[4bvt]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4bvt]] is a 2 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zgu 3zgu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BVT FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4bvt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_sp._ADP Pseudomonas sp. ADP]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3zgu 3zgu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BVT FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BR8:BARBITURIC+ACID'>BR8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4bvq|4bvq]], [[4bvr|4bvr]], [[4bvs|4bvs]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR8:BARBITURIC+ACID'>BR8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyanuric_acid_amidohydrolase Cyanuric acid amidohydrolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.15 3.5.2.15] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bvt OCA], [https://pdbe.org/4bvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bvt RCSB], [https://www.ebi.ac.uk/pdbsum/4bvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bvt ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bvt OCA], [http://pdbe.org/4bvt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4bvt RCSB], [http://www.ebi.ac.uk/pdbsum/4bvt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4bvt ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CAH_PSESD CAH_PSESD] Responsible for the hydrolysis of cyanuric acid, an intermediate formed during catabolism of s-triazine based compounds in herbicides such as atrazine and polymers such as melamine. Catalyzes the hydrolytic opening of the s-triazine ring of cyanuric acid (2,4,6-trihydroxy-s-triazine) to yield carbon dioxide and carboxybiuret, which spontaneously decarboxylates to biuret.[HAMAP-Rule:MF_01989]<ref>PMID:11544232</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cyanuric acid amidohydrolase]]
+
[[Category: Large Structures]]
-
[[Category: Balotra, S]]
+
[[Category: Pseudomonas sp. ADP]]
-
[[Category: Briggs, L J]]
+
[[Category: Balotra S]]
-
[[Category: Cowieson, N]]
+
[[Category: Briggs LJ]]
-
[[Category: French, N G]]
+
[[Category: Cowieson N]]
-
[[Category: Newman, J]]
+
[[Category: French NG]]
-
[[Category: Panjikar, S]]
+
[[Category: Newman J]]
-
[[Category: Peat, T S]]
+
[[Category: Panjikar S]]
-
[[Category: Scott, C]]
+
[[Category: Peat TS]]
-
[[Category: Wilding, M]]
+
[[Category: Scott C]]
-
[[Category: Amidase]]
+
[[Category: Wilding M]]
-
[[Category: Hydrolase]]
+

Current revision

Cyanuric acid hydrolase: evolutionary innovation by structural concatenation

PDB ID 4bvt

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bvt"
Personal tools