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4ck4
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4ck4 is ON HOLD Authors: Kontopidis, G., Nordle, A., Sawyer, L. Description: Ovine beta-Lactoglobulin at Atomic Resolution) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Ovine beta-Lactoglobulin at Atomic Resolution== | |
| + | <StructureSection load='4ck4' size='340' side='right'caption='[[4ck4]], [[Resolution|resolution]] 1.12Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4ck4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ovis_aries Ovis aries]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CK4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CK4 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.12Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ck4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ck4 OCA], [https://pdbe.org/4ck4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ck4 RCSB], [https://www.ebi.ac.uk/pdbsum/4ck4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ck4 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LACB_SHEEP LACB_SHEEP] Lactoglobulin is the primary component of whey, it binds retinol and is probably involved in the transport of that molecule. | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The crystal structure of the triclinic form of the milk protein beta-lactoglobulin from sheep (Ovis aries) at 1.1 A resolution is described together with a comparison of the triclinic structures of the low-pH bovine and high-pH ovine proteins. All three structures are remarkably similar, despite the well known pH-dependent conformational transition described for the bovine and porcine proteins that occurs in solution. The high resolution of the present structure determination has allowed a more accurate description of the protein than has hitherto been possible, but it is still not clear whether flexibility changes in the external loops can compensate for the presence of a significant void in the unliganded interior of the structure. | ||
| - | + | Ovine beta-lactoglobulin at atomic resolution.,Kontopidis G, Nordle Gilliver A, Sawyer L Acta Crystallogr F Struct Biol Commun. 2014 Nov;70(Pt 11):1498-503. doi:, 10.1107/S2053230X14020950. Epub 2014 Oct 31. PMID:25372816<ref>PMID:25372816</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| + | </div> | ||
| + | <div class="pdbe-citations 4ck4" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Beta-lactoglobulin 3D structures|Beta-lactoglobulin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Ovis aries]] | ||
| + | [[Category: Kontopidis G]] | ||
| + | [[Category: Nordle A]] | ||
| + | [[Category: Sawyer L]] | ||
Current revision
Ovine beta-Lactoglobulin at Atomic Resolution
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