This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4d60

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:21, 20 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Structure of a dimeric Plasmodium falciparum profilin mutant==
==Structure of a dimeric Plasmodium falciparum profilin mutant==
-
<StructureSection load='4d60' size='340' side='right' caption='[[4d60]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
+
<StructureSection load='4d60' size='340' side='right'caption='[[4d60]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4d60]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D60 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4D60 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4d60]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D60 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4d60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d60 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4d60 RCSB], [http://www.ebi.ac.uk/pdbsum/4d60 PDBsum]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d60 OCA], [https://pdbe.org/4d60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d60 RCSB], [https://www.ebi.ac.uk/pdbsum/4d60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d60 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PROF_PLAFX PROF_PLAFX]] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers.<ref>PMID:19000816</ref>
+
[https://www.uniprot.org/uniprot/PROF_PLAF7 PROF_PLAF7] Essential for the invasive blood stages of the parasite. Binds to proline rich sequences in various regulatory formin-like proteins and also to membrane phospholipids. Binds to actin and affects the structure of the cytoskeleton. Weakly sequesters actin monomers (By similarity).[UniProtKB:P86294]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4d60" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[Profilin 3D Structures|Profilin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Bhargav, S P]]
+
[[Category: Large Structures]]
-
[[Category: Kallio, J P]]
+
[[Category: Plasmodium falciparum]]
-
[[Category: Kursula, I]]
+
[[Category: Bhargav SP]]
-
[[Category: Kursula, P]]
+
[[Category: Kallio JP]]
-
[[Category: Torda, A]]
+
[[Category: Kursula I]]
-
[[Category: Vahokoski, J]]
+
[[Category: Kursula P]]
-
[[Category: Actin binding]]
+
[[Category: Torda A]]
-
[[Category: Domain swapping]]
+
[[Category: Vahokoski J]]
-
[[Category: Structural protein]]
+

Current revision

Structure of a dimeric Plasmodium falciparum profilin mutant

PDB ID 4d60

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4d60"
Personal tools