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4u2k

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<StructureSection load='4u2k' size='340' side='right'caption='[[4u2k]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
<StructureSection load='4u2k' size='340' side='right'caption='[[4u2k]], [[Resolution|resolution]] 2.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4u2k]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillo_virgola_del_koch"_trevisan_1884 "bacillo virgola del koch" trevisan 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U2K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U2K FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4u2k]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U2K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U2K FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4WR:1-[(2R)-2,3-DIAMINOPROPYL]-5-FLUOROPYRIMIDINE-2,4(1H,3H)-DIONE'>4WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=M5F:1-[(2S)-2,3-DIAMINOPROPYL]-5-FLUOROPYRIMIDINE-2,4(1H,3H)-DIONE'>M5F</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.13&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4h1t|4h1t]], [[4k6o|4k6o]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4WR:1-[(2R)-2,3-DIAMINOPROPYL]-5-FLUOROPYRIMIDINE-2,4(1H,3H)-DIONE'>4WR</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=M5F:1-[(2S)-2,3-DIAMINOPROPYL]-5-FLUOROPYRIMIDINE-2,4(1H,3H)-DIONE'>M5F</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">udp, DN30_1909, VC39_02535, VC78_02550, VS27_10630, WG08_05660 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 "Bacillo virgola del Koch" Trevisan 1884])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u2k OCA], [https://pdbe.org/4u2k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u2k RCSB], [https://www.ebi.ac.uk/pdbsum/4u2k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u2k ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Uridine_phosphorylase Uridine phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.3 2.4.2.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u2k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u2k OCA], [http://pdbe.org/4u2k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u2k RCSB], [http://www.ebi.ac.uk/pdbsum/4u2k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u2k ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q9K4U1_VIBCL Q9K4U1_VIBCL]
==See Also==
==See Also==
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*[[Uridine phosphorylase|Uridine phosphorylase]]
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*[[Uridine phosphorylase 3D structures|Uridine phosphorylase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillo virgola del koch trevisan 1884]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Uridine phosphorylase]]
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[[Category: Vibrio cholerae]]
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[[Category: Betzel, C]]
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[[Category: Betzel C]]
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[[Category: Gabdoulkhakov, A G]]
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[[Category: Gabdoulkhakov AG]]
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[[Category: Lashkov, A A]]
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[[Category: Lashkov AA]]
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[[Category: Mikhailov, A M]]
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[[Category: Mikhailov AM]]
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[[Category: Prokofev, I I]]
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[[Category: Prokofev II]]
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[[Category: Rossmann fold]]
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[[Category: Transferase]]
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Current revision

X-ray structure uridine phosphorylase from Vibrio cholerae in complex with anticancer compound at 2.13 A resolution

PDB ID 4u2k

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