This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4u3d

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:26, 20 December 2023) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==LpxC from A.Aaeolicus in complex with 4-[[4-[2-[4-(morpholinomethyl)phenyl]ethynyl]phenoxy]methyl]tetrahydropyran-4-carbohydroxamic acid (compound 9)==
==LpxC from A.Aaeolicus in complex with 4-[[4-[2-[4-(morpholinomethyl)phenyl]ethynyl]phenoxy]methyl]tetrahydropyran-4-carbohydroxamic acid (compound 9)==
-
<StructureSection load='4u3d' size='340' side='right' caption='[[4u3d]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
+
<StructureSection load='4u3d' size='340' side='right'caption='[[4u3d]], [[Resolution|resolution]] 1.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4u3d]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4U3D FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4u3d]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U3D FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3BX:N-HYDROXY-4-[(4-{[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ETHYNYL}PHENOXY)METHYL]TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE'>3BX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4u3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3d OCA], [http://pdbe.org/4u3d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4u3d RCSB], [http://www.ebi.ac.uk/pdbsum/4u3d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3d ProSAT]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3BX:N-HYDROXY-4-[(4-{[4-(MORPHOLIN-4-YLMETHYL)PHENYL]ETHYNYL}PHENOXY)METHYL]TETRAHYDRO-2H-PYRAN-4-CARBOXAMIDE'>3BX</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u3d OCA], [https://pdbe.org/4u3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u3d RCSB], [https://www.ebi.ac.uk/pdbsum/4u3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u3d ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
+
[https://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 18: Line 19:
</div>
</div>
<div class="pdbe-citations 4u3d" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 4u3d" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Olivier, N B]]
+
[[Category: Aquifex aeolicus VF5]]
-
[[Category: Antibacterial]]
+
[[Category: Large Structures]]
-
[[Category: Gram negative bacteria]]
+
[[Category: Olivier NB]]
-
[[Category: Hydrolase]]
+
-
[[Category: Hydrophobe]]
+
-
[[Category: Lpxc]]
+
-
[[Category: Mmp]]
+

Current revision

LpxC from A.Aaeolicus in complex with 4-[[4-[2-[4-(morpholinomethyl)phenyl]ethynyl]phenoxy]methyl]tetrahydropyran-4-carbohydroxamic acid (compound 9)

PDB ID 4u3d

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4u3d"
Personal tools