This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
4u55
From Proteopedia
(Difference between revisions)
| (9 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Crystal structure of Cryptopleurine bound to the yeast 80S ribosome== | ==Crystal structure of Cryptopleurine bound to the yeast 80S ribosome== | ||
| - | <StructureSection load='4u55' size='340' side='right' caption='[[4u55]], [[Resolution|resolution]] 3.20Å' scene=''> | + | <StructureSection load='4u55' size='340' side='right'caption='[[4u55]], [[Resolution|resolution]] 3.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4u55]] is a | + | <table><tr><td colspan='2'>[[4u55]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. This structure supersedes the now removed PDB entries [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukk 4ukk], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukl 4ukl], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukm 4ukm], [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4ukn 4ukn] and [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4uko 4uko]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4U55 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4U55 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3K8:(14AR)-2,3,6-TRIMETHOXY-11,12,13,14,14A,15-HEXAHYDRO-9H-DIBENZO[F,H]PYRIDO[1,2-B]ISOQUINOLINE'>3K8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3K8:(14AR)-2,3,6-TRIMETHOXY-11,12,13,14,14A,15-HEXAHYDRO-9H-DIBENZO[F,H]PYRIDO[1,2-B]ISOQUINOLINE'>3K8</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=OHX:OSMIUM+(III)+HEXAMMINE'>OHX</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4u55 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4u55 OCA], [https://pdbe.org/4u55 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4u55 RCSB], [https://www.ebi.ac.uk/pdbsum/4u55 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4u55 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RS10A_YEAST RS10A_YEAST] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 16: | Line 18: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4u55" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Ribosome 3D structures|Ribosome 3D structures]] | *[[Ribosome 3D structures|Ribosome 3D structures]] | ||
| + | *[[3D sructureseceptor for activated protein kinase C 1|3D sructureseceptor for activated protein kinase C 1]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Saccharomyces cerevisiae | + | [[Category: Large Structures]] |
| - | [[Category: Loubresse | + | [[Category: Saccharomyces cerevisiae S288C]] |
| - | [[Category: Prokhorova | + | [[Category: Garreau de Loubresse N]] |
| - | [[Category: Yusupov | + | [[Category: Prokhorova I]] |
| - | [[Category: Yusupova | + | [[Category: Yusupov M]] |
| - | + | [[Category: Yusupova G]] | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of Cryptopleurine bound to the yeast 80S ribosome
| |||||||||||
