This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2kbp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:50, 20 December 2023) (edit) (undo)
 
(8 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:2kbp.jpg|left|200px]]
 
-
<!--
+
==Solution structure of a G-quadruplex of human telomeric RNA==
-
The line below this paragraph, containing "STRUCTURE_2kbp", creates the "Structure Box" on the page.
+
<StructureSection load='2kbp' size='340' side='right'caption='[[2kbp]]' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[2kbp]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KBP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KBP FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kbp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kbp OCA], [https://pdbe.org/2kbp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kbp RCSB], [https://www.ebi.ac.uk/pdbsum/2kbp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kbp ProSAT]</span></td></tr>
-
{{STRUCTURE_2kbp| PDB=2kbp | SCENE= }}
+
</table>
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Very recent studies showed that mammalian telomeres were transcribed into telomeric-repeat-containing RNAs and suggested that these RNA molecules were biologically important. Here we report on a structural study of RNA G-quadruplexes formed by human telomeric RNA sequences in K(+) solution. Our data indicated that these sequences formed propeller-type parallel-stranded RNA G-quadruplexes. We have determined the NMR-based solution structure of a dimeric propeller-type RNA G-quadruplex formed by the 12-nt human telomeric RNA sequence r(UAGGGUUAGGGU). We also observed the stacking of two such propeller-type G-quadruplex blocks for the 10-nt human telomeric RNA sequence r(GGGUUAGGGU) and a higher-order G-quadruplex structure for the 9-nt human telomeric RNA sequence r(GGGUUAGGG). Based on these findings we proposed how higher-order structures might be formed by long telomeric RNA.
-
===Solution structure of a G-quadruplex of human telomeric RNA===
+
Structure of propeller-type parallel-stranded RNA G-quadruplexes, formed by human telomeric RNA sequences in K+ solution.,Martadinata H, Phan AT J Am Chem Soc. 2009 Feb 25;131(7):2570-8. PMID:19183046<ref>PMID:19183046</ref>
-
 
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
<!--
+
</div>
-
The line below this paragraph, {{ABSTRACT_PUBMED_19183046}}, adds the Publication Abstract to the page
+
<div class="pdbe-citations 2kbp" style="background-color:#fffaf0;"></div>
-
(as it appears on PubMed at http://www.pubmed.gov), where 19183046 is the PubMed ID number.
+
== References ==
-
-->
+
<references/>
-
{{ABSTRACT_PUBMED_19183046}}
+
__TOC__
-
 
+
</StructureSection>
-
==About this Structure==
+
[[Category: Large Structures]]
-
2KBP is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KBP OCA].
+
[[Category: Martadinata H]]
-
 
+
[[Category: Phan AT]]
-
==Reference==
+
-
<ref group="xtra">PMID:19183046</ref><references group="xtra"/>
+
-
[[Category: Martadinata, H.]]
+
-
[[Category: Phan, A T.]]
+
-
[[Category: G-quadruplex]]
+
-
[[Category: Parallel form]]
+
-
[[Category: Rna]]
+
-
[[Category: Telomeric]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 25 12:07:57 2009''
+

Current revision

Solution structure of a G-quadruplex of human telomeric RNA

PDB ID 2kbp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2kbp"
Personal tools