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8i7q

From Proteopedia

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m (Protected "8i7q" [edit=sysop:move=sysop])
Current revision (23:12, 27 December 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8i7q is ON HOLD
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==Cobalt and Calcium coordinated Concanavalin A at pH 7.4 from Canavalia ensiformis==
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<StructureSection load='8i7q' size='340' side='right'caption='[[8i7q]], [[Resolution|resolution]] 2.83&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8i7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Canavalia_ensiformis Canavalia ensiformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I7Q FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.83&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i7q OCA], [https://pdbe.org/8i7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i7q RCSB], [https://www.ebi.ac.uk/pdbsum/8i7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i7q ProSAT]</span></td></tr>
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</table>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Concanavalin A (ConA) has an intrinsic binding affinity to carbohydrates. Here, we obtained Co(2+)-Ca(2+)-ConA (2.83 A, PDB: 8I7Q) via X-ray crystallography by substituting native ConA (Mn(2+)-Ca(2+)); it has binding selectivity for high-mannose N-glycan similar to native ConA. Our findings may thus inform antiviral reagent design.
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Authors: Hwang, Y., Jeong, J.H., Lee, S.J.
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Selective interactions of Co(2+)-Ca(2+)-concanavalin A with high mannose N-glycans.,Hwang Y, Jeong JH, Lee DH, Lee SJ Dalton Trans. 2023 Dec 12. doi: 10.1039/d3dt03575a. PMID:38086668<ref>PMID:38086668</ref>
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Description: Cobalt and Calcium coordinated Concanavalin A at pH 7.4 from Canavalia ensiformis
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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[[Category: Unreleased Structures]]
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</div>
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[[Category: Hwang, Y]]
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<div class="pdbe-citations 8i7q" style="background-color:#fffaf0;"></div>
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[[Category: Lee, S.J]]
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== References ==
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[[Category: Jeong, J.H]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Canavalia ensiformis]]
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[[Category: Large Structures]]
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[[Category: Hwang Y]]
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[[Category: Jeong JH]]
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[[Category: Lee SJ]]

Current revision

Cobalt and Calcium coordinated Concanavalin A at pH 7.4 from Canavalia ensiformis

PDB ID 8i7q

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