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1flm

From Proteopedia

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[[Image:1flm.png|left|200px]]
 
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{{STRUCTURE_1flm| PDB=1flm | SCENE= }}
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==DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)==
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<StructureSection load='1flm' size='340' side='right'caption='[[1flm]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1flm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'Miyazaki_F' Desulfovibrio vulgaris str. 'Miyazaki F']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLM FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flm OCA], [https://pdbe.org/1flm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flm RCSB], [https://www.ebi.ac.uk/pdbsum/1flm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flm ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FMNB_DESVM FMNB_DESVM] Functions as a redox protein with a potential of -325 mV.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flm_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1flm ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The crystal structure of FMN-binding protein (FMN-bp) from Desulfovibrio vulgaris Miyazaki F was solved by the multiple isomorphous replacement method and refined to an R factor of 15.1% at 1.3 A resolution. FMN-bp exists in a dimeric form in the crystal, in contrast to the monomeric structure determined by NMR. R.m.s. deviations between the crystal structure and the solution structure are more than 2 A, which implies significant differences. There are some hydrophobic residues in the interface between the two monomers. In particular, Leu122 in the C-terminus has a close contact with the o-xylene moiety of FMN, while solvent molecules may cover the o-xylene moiety in the solution structure.
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===DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)===
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How do the x-ray structure and the NMR structure of FMN-binding protein differ?,Suto K, Kawagoe K, Shibata N, Morimoto Y, Higuchi Y, Kitamura M, Nakaya T, Yasuoka N Acta Crystallogr D Biol Crystallogr. 2000 Mar;56(Pt 3):368-71. PMID:10713530<ref>PMID:10713530</ref>
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{{ABSTRACT_PUBMED_10713530}}
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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==About this Structure==
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<div class="pdbe-citations 1flm" style="background-color:#fffaf0;"></div>
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[[1flm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_vulgaris_str._'miyazaki_f' Desulfovibrio vulgaris str. 'miyazaki f']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLM OCA].
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== References ==
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<references/>
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==Reference==
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__TOC__
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<ref group="xtra">PMID:010713530</ref><ref group="xtra">PMID:015608121</ref><references group="xtra"/>
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</StructureSection>
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[[Category: Desulfovibrio vulgaris str. 'miyazaki f']]
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[[Category: Desulfovibrio vulgaris str. 'Miyazaki F']]
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[[Category: Higuchi, Y.]]
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[[Category: Large Structures]]
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[[Category: Kawagoe, K.]]
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[[Category: Higuchi Y]]
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[[Category: Kitamura, M.]]
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[[Category: Kawagoe K]]
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[[Category: Morimoto, K.]]
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[[Category: Kitamura M]]
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[[Category: Nakaya, T.]]
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[[Category: Morimoto K]]
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[[Category: Shibata, N.]]
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[[Category: Nakaya T]]
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[[Category: Suto, K.]]
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[[Category: Shibata N]]
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[[Category: Yasuoka, N.]]
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[[Category: Suto K]]
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[[Category: Electron transport]]
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[[Category: Yasuoka N]]
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[[Category: Fmn binding]]
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Current revision

DIMER OF FMN-BINDING PROTEIN FROM DESULFOVIBRIO VULGARIS (MIYAZAKI F)

PDB ID 1flm

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