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1iq3

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==SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OF A HUMAN POB1==
==SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OF A HUMAN POB1==
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<StructureSection load='1iq3' size='340' side='right' caption='[[1iq3]], [[NMR_Ensembles_of_Models | 18 NMR models]]' scene=''>
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<StructureSection load='1iq3' size='340' side='right'caption='[[1iq3]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1iq3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IQ3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IQ3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1iq3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IQ3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iq3 OCA], [http://pdbe.org/1iq3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iq3 RCSB], [http://www.ebi.ac.uk/pdbsum/1iq3 PDBsum], [http://www.topsan.org/Proteins/RSGI/1iq3 TOPSAN]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iq3 OCA], [https://pdbe.org/1iq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iq3 RCSB], [https://www.ebi.ac.uk/pdbsum/1iq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iq3 ProSAT], [https://www.topsan.org/Proteins/RSGI/1iq3 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/REPS2_HUMAN REPS2_HUMAN]] Involved in growth factor signaling through its influence on the Ral signaling pathway.
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[https://www.uniprot.org/uniprot/REPS2_HUMAN REPS2_HUMAN] Involved in growth factor signaling through its influence on the Ral signaling pathway.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/1iq3_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iq/1iq3_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iq3 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Iwahara, J]]
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[[Category: Large Structures]]
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[[Category: Kigawa, T]]
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[[Category: Iwahara J]]
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[[Category: Kikuchi, A]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S]]
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[[Category: Kikuchi A]]
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[[Category: Structural genomic]]
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[[Category: Koshiba S]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Ef-hand domain]]
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[[Category: Endocytosis-exocytosis complex]]
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[[Category: Pob1 eh domain]]
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[[Category: Rsgi]]
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Current revision

SOLUTION STRUCTURE OF THE EPS15 HOMOLOGY DOMAIN OF A HUMAN POB1

PDB ID 1iq3

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