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1iy9
From Proteopedia
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| - | [[Image:1iy9.gif|left|200px]]<br /><applet load="1iy9" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1iy9, resolution 2.30Å" /> | ||
| - | '''Crystal structure of spermidine synthase'''<br /> | ||
| - | == | + | ==Crystal structure of spermidine synthase== |
| - | + | <StructureSection load='1iy9' size='340' side='right'caption='[[1iy9]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | [ | + | == Structural highlights == |
| - | [[ | + | <table><tr><td colspan='2'>[[1iy9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IY9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IY9 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iy9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iy9 OCA], [https://pdbe.org/1iy9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iy9 RCSB], [https://www.ebi.ac.uk/pdbsum/1iy9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iy9 ProSAT], [https://www.topsan.org/Proteins/NESGC/1iy9 TOPSAN]</span></td></tr> |
| - | [ | + | </table> |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/SPEE_BACSU SPEE_BACSU] Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine (Probable).<ref>PMID:9723923</ref> |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iy/1iy9_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iy9 ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | + | ||
| - | + | ==See Also== | |
| + | *[[Spermidine synthase 3D structures|Spermidine synthase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus subtilis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Acton T]] | ||
| + | [[Category: Hunt JF]] | ||
| + | [[Category: Montelione G]] | ||
| + | [[Category: Rost B]] | ||
| + | [[Category: Shen J]] | ||
| + | [[Category: Smith PC]] | ||
| + | [[Category: Tan AY]] | ||
| + | [[Category: Xiao R]] | ||
Current revision
Crystal structure of spermidine synthase
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Categories: Bacillus subtilis | Large Structures | Acton T | Hunt JF | Montelione G | Rost B | Shen J | Smith PC | Tan AY | Xiao R
