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1j05
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==The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment== | ==The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment== | ||
| - | <StructureSection load='1j05' size='340' side='right' caption='[[1j05]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='1j05' size='340' side='right'caption='[[1j05]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1j05]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1j05]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J05 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j05 OCA], [https://pdbe.org/1j05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j05 RCSB], [https://www.ebi.ac.uk/pdbsum/1j05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j05 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KV3A8_MOUSE KV3A8_MOUSE] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j0/1j05_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j0/1j05_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j05 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Monoclonal | + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Asano | + | [[Category: Mus musculus]] |
| - | [[Category: Kondo | + | [[Category: Asano R]] |
| - | [[Category: Kumagai | + | [[Category: Kondo H]] |
| - | [[Category: Nishimura | + | [[Category: Kumagai I]] |
| - | [[Category: Noro | + | [[Category: Nishimura Y]] |
| - | [[Category: Shiroishi | + | [[Category: Noro N]] |
| - | [[Category: Tsumoto | + | [[Category: Shiroishi M]] |
| - | + | [[Category: Tsumoto K]] | |
| - | + | ||
Current revision
The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
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Categories: Large Structures | Mus musculus | Asano R | Kondo H | Kumagai I | Nishimura Y | Noro N | Shiroishi M | Tsumoto K
