This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1j05
From Proteopedia
(Difference between revisions)
(New page: 200px<br /> <applet load="1j05" size="450" color="white" frame="true" align="right" spinBox="true" caption="1j05, resolution 1.50Å" /> '''The crystal structu...) |
|||
| (16 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:1j05.gif|left|200px]]<br /> | ||
| - | <applet load="1j05" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1j05, resolution 1.50Å" /> | ||
| - | '''The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment'''<br /> | ||
| - | == | + | ==The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment== |
| - | + | <StructureSection load='1j05' size='340' side='right'caption='[[1j05]], [[Resolution|resolution]] 1.50Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [[ | + | <table><tr><td colspan='2'>[[1j05]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J05 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J05 FirstGlance]. <br> |
| - | [[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j05 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j05 OCA], [https://pdbe.org/1j05 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j05 RCSB], [https://www.ebi.ac.uk/pdbsum/1j05 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j05 ProSAT]</span></td></tr> |
| - | + | </table> | |
| - | [ | + | == Function == |
| - | [ | + | [https://www.uniprot.org/uniprot/KV3A8_MOUSE KV3A8_MOUSE] |
| - | [[ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | [ | + | <jmolCheckbox> |
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j0/1j05_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j05 ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Asano R]] | ||
| + | [[Category: Kondo H]] | ||
| + | [[Category: Kumagai I]] | ||
| + | [[Category: Nishimura Y]] | ||
| + | [[Category: Noro N]] | ||
| + | [[Category: Shiroishi M]] | ||
| + | [[Category: Tsumoto K]] | ||
Current revision
The crystal structure of anti-carcinoembryonic antigen monoclonal antibody T84.66 Fv fragment
| |||||||||||
Categories: Large Structures | Mus musculus | Asano R | Kondo H | Kumagai I | Nishimura Y | Noro N | Shiroishi M | Tsumoto K
