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1j1o

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==Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme==
==Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme==
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<StructureSection load='1j1o' size='340' side='right' caption='[[1j1o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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<StructureSection load='1j1o' size='340' side='right'caption='[[1j1o]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1j1o]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1J1O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1j1o]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J1O FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c08|1c08]], [[1j1p|1j1p]], [[1j1x|1j1x]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1o OCA], [https://pdbe.org/1j1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j1o RCSB], [https://www.ebi.ac.uk/pdbsum/1j1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j1o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1j1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j1o OCA], [http://pdbe.org/1j1o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1j1o RCSB], [http://www.ebi.ac.uk/pdbsum/1j1o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1j1o ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>
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[https://www.uniprot.org/uniprot/KV5A9_MOUSE KV5A9_MOUSE]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
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*[[3D structures of monoclonal antibody|3D structures of monoclonal antibody]]
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*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Lysozyme]]
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[[Category: Mus musculus]]
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[[Category: Kondo, H]]
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[[Category: Kondo H]]
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[[Category: Kumagai, I]]
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[[Category: Kumagai I]]
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[[Category: Shiroishi, M]]
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[[Category: Shiroishi M]]
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[[Category: Tsumoto, K]]
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[[Category: Tsumoto K]]
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[[Category: Yokota, A]]
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[[Category: Yokota A]]
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[[Category: Antigen-antibody complex]]
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[[Category: Immune system-hydrolase complex]]
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Current revision

Crystal Structure of HyHEL-10 Fv mutant LY50F complexed with hen egg white lysozyme

PDB ID 1j1o

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