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1j3c

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{{Seed}}
 
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[[Image:1j3c.png|left|200px]]
 
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==Solution structure of the C-terminal domain of the HMGB2==
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The line below this paragraph, containing "STRUCTURE_1j3c", creates the "Structure Box" on the page.
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<StructureSection load='1j3c' size='340' side='right'caption='[[1j3c]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1j3c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J3C FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j3c OCA], [https://pdbe.org/1j3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j3c RCSB], [https://www.ebi.ac.uk/pdbsum/1j3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j3c ProSAT]</span></td></tr>
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{{STRUCTURE_1j3c| PDB=1j3c | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HMGB2_PIG HMGB2_PIG] DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS) (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j3/1j3c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j3c ConSurf].
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<div style="clear:both"></div>
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===Solution structure of the C-terminal domain of the HMGB2===
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==See Also==
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*[[High mobility group protein|High mobility group protein]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1J3C is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J3C OCA].
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
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[[Category: Kurita, J.]]
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[[Category: Kurita J]]
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[[Category: Shimahara, H.]]
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[[Category: Shimahara H]]
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[[Category: Tate, S.]]
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[[Category: Tate S]]
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[[Category: Yoshida, M.]]
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[[Category: Yoshida M]]
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[[Category: Hmg-box]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 14:26:22 2008''
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Current revision

Solution structure of the C-terminal domain of the HMGB2

PDB ID 1j3c

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