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1j48
From Proteopedia
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<StructureSection load='1j48' size='340' side='right'caption='[[1j48]], [[Resolution|resolution]] 1.80Å' scene=''> | <StructureSection load='1j48' size='340' side='right'caption='[[1j48]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J48 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j48 OCA], [https://pdbe.org/1j48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j48 RCSB], [https://www.ebi.ac.uk/pdbsum/1j48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j48 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/CAGA_STRGL CAGA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Actinomyces globisporus krasil'nikov 1941]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bartlam | + | [[Category: Streptomyces globisporus]] |
| - | [[Category: Chen | + | [[Category: Bartlam M]] |
| - | [[Category: Gao | + | [[Category: Chen Y]] |
| - | [[Category: Jin | + | [[Category: Gao Y]] |
| - | [[Category: Li | + | [[Category: Jin L]] |
| - | [[Category: Liu | + | [[Category: Li J]] |
| - | [[Category: Rao | + | [[Category: Liu Y]] |
| - | [[Category: Shao | + | [[Category: Rao Z]] |
| - | [[Category: Tang | + | [[Category: Shao Y]] |
| - | [[Category: Zhen | + | [[Category: Tang H]] |
| - | + | [[Category: Zhen Y]] | |
| - | + | ||
Current revision
Crystal Structure of Apo-C1027
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Categories: Large Structures | Streptomyces globisporus | Bartlam M | Chen Y | Gao Y | Jin L | Li J | Liu Y | Rao Z | Shao Y | Tang H | Zhen Y
