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1j48

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{{Seed}}
 
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[[Image:1j48.png|left|200px]]
 
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==Crystal Structure of Apo-C1027==
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The line below this paragraph, containing "STRUCTURE_1j48", creates the "Structure Box" on the page.
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<StructureSection load='1j48' size='340' side='right'caption='[[1j48]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1j48]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J48 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j48 OCA], [https://pdbe.org/1j48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j48 RCSB], [https://www.ebi.ac.uk/pdbsum/1j48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j48 ProSAT]</span></td></tr>
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{{STRUCTURE_1j48| PDB=1j48 | SCENE= }}
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</table>
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== Function ==
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===Crystal Structure of Apo-C1027===
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[https://www.uniprot.org/uniprot/CAGA_STRGL CAGA_STRGL] Binds non-covalently to a chromophore which is the cytotoxic and mutagenic component of the antibiotic. The chromophore binds to DNA as a weak intercalator and causes single- and double-strand breaks.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1J48 is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Streptomyces_globisporus Streptomyces globisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J48 OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/1j48_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j48 ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Streptomyces globisporus]]
[[Category: Streptomyces globisporus]]
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[[Category: Bartlam, M.]]
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[[Category: Bartlam M]]
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[[Category: Chen, Y.]]
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[[Category: Chen Y]]
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[[Category: Gao, Y.]]
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[[Category: Gao Y]]
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[[Category: Jin, L.]]
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[[Category: Jin L]]
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[[Category: Li, J.]]
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[[Category: Li J]]
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[[Category: Liu, Y.]]
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[[Category: Liu Y]]
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[[Category: Rao, Z.]]
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[[Category: Rao Z]]
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[[Category: Shao, Y.]]
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[[Category: Shao Y]]
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[[Category: Tang, H.]]
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[[Category: Tang H]]
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[[Category: Zhen, Y.]]
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[[Category: Zhen Y]]
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[[Category: Antibiotic]]
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[[Category: Dna-binding]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 10:09:07 2009''
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Current revision

Crystal Structure of Apo-C1027

PDB ID 1j48

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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