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1j5u
From Proteopedia
(Difference between revisions)
(New page: 200px<br /><applet load="1j5u" size="450" color="white" frame="true" align="right" spinBox="true" caption="1j5u, resolution 2.00Å" /> '''Crystal structure of...) |
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| - | [[Image:1j5u.gif|left|200px]]<br /><applet load="1j5u" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="1j5u, resolution 2.00Å" /> | ||
| - | '''Crystal structure of archease, possible chaperone (TM1083) from Thermotoga maritima at 2.0 A resolution'''<br /> | ||
| - | == | + | ==CRYSTAL STRUCTURE OF AN ARCHEASE, POSSIBLE CHAPERONE (TM1083) FROM THERMOTOGA MARITIMA AT 2.0 A RESOLUTION== |
| - | + | <StructureSection load='1j5u' size='340' side='right'caption='[[1j5u]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | [[ | + | == Structural highlights == |
| + | <table><tr><td colspan='2'>[[1j5u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J5U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j5u OCA], [https://pdbe.org/1j5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j5u RCSB], [https://www.ebi.ac.uk/pdbsum/1j5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j5u ProSAT], [https://www.topsan.org/Proteins/JCSG/1j5u TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ARCH_THEMA ARCH_THEMA] Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently (By similarity). May also act as a chaperone or modulator of proteins involved in DNA or RNA processing. | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j5/1j5u_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j5u ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
| - | [[Category: JCSG, Joint.Center.for.Structural.Genomics.]] | ||
| - | [[Category: CA]] | ||
| - | [[Category: archease]] | ||
| - | [[Category: jcsg]] | ||
| - | [[Category: joint center for structural genomics]] | ||
| - | [[Category: possible chaperone]] | ||
| - | [[Category: protein structure initiative]] | ||
| - | [[Category: psi]] | ||
| - | [[Category: structural genomics]] | ||
| - | [[Category: tm1083]] | ||
| - | |||
| - | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sat Nov 24 23:09:35 2007'' | ||
Current revision
CRYSTAL STRUCTURE OF AN ARCHEASE, POSSIBLE CHAPERONE (TM1083) FROM THERMOTOGA MARITIMA AT 2.0 A RESOLUTION
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