This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1ufn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (23:52, 27 December 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1ufn.jpg|left|200px]]
 
-
{{Structure
+
==Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)==
-
|PDB= 1ufn |SIZE=350|CAPTION= <scene name='initialview01'>1ufn</scene>
+
<StructureSection load='1ufn' size='340' side='right'caption='[[1ufn]]' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1ufn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UFN FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
|GENE= RIKEN cDNA 5830484A20 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ufn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ufn OCA], [https://pdbe.org/1ufn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ufn RCSB], [https://www.ebi.ac.uk/pdbsum/1ufn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ufn ProSAT], [https://www.topsan.org/Proteins/RSGI/1ufn TOPSAN]</span></td></tr>
-
}}
+
</table>
-
 
+
== Disease ==
-
'''Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)'''
+
[https://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE] Defects in Sp110 are a cause of severely impaired resistance to infection by M.tuberculosis.<ref>PMID:15815631</ref>
-
 
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/SP110_MOUSE SP110_MOUSE] May act as a transcription factor. Plays a role in the innate immunity against intracellular pathogens. Required for resistance to M.tuberculosis and L.monocytogenes. Promotes apoptosis of infected cells.<ref>PMID:15815631</ref>
-
==About this Structure==
+
== Evolutionary Conservation ==
-
1UFN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UFN OCA].
+
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uf/1ufn_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ufn ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Single protein]]
+
[[Category: Aoki M]]
-
[[Category: Aoki, M.]]
+
[[Category: Arakawa T]]
-
[[Category: Arakawa, T.]]
+
[[Category: Carninci P]]
-
[[Category: Carninci, P.]]
+
[[Category: Hayashizaki Y]]
-
[[Category: Hayashizaki, Y.]]
+
[[Category: Hirota H]]
-
[[Category: Hirota, H.]]
+
[[Category: Inoue M]]
-
[[Category: Inoue, M.]]
+
[[Category: Kawai J]]
-
[[Category: Kawai, J.]]
+
[[Category: Kigawa T]]
-
[[Category: Kigawa, T.]]
+
[[Category: Kobayashi N]]
-
[[Category: Kobayashi, N.]]
+
[[Category: Koshiba S]]
-
[[Category: Koshiba, S.]]
+
[[Category: Matsuda T]]
-
[[Category: Matsuda, T.]]
+
[[Category: Matsuo Y]]
-
[[Category: Matsuo, Y.]]
+
[[Category: Osanai T]]
-
[[Category: Osanai, T.]]
+
[[Category: Seki E]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Shirouzu M]]
-
[[Category: Seki, E.]]
+
[[Category: Tanaka A]]
-
[[Category: Shirouzu, M.]]
+
[[Category: Terada T]]
-
[[Category: Tanaka, A.]]
+
[[Category: Tochio N]]
-
[[Category: Terada, T.]]
+
[[Category: Yabuki T]]
-
[[Category: Tochio, N.]]
+
[[Category: Yokoyama S]]
-
[[Category: Yabuki, T.]]
+
[[Category: Yoshida M]]
-
[[Category: Yokoyama, S.]]
+
-
[[Category: Yoshida, M.]]
+
-
[[Category: kdwk motif]]
+
-
[[Category: nuclear protein]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: sand domain]]
+
-
[[Category: structural genomic]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:31:21 2008''
+

Current revision

Solution structure of the SAND domain of the putative nuclear protein homolog (5830484A20Rik)

PDB ID 1ufn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1ufn"
Personal tools