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1ugo

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==Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5==
==Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5==
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<StructureSection load='1ugo' size='340' side='right' caption='[[1ugo]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1ugo' size='340' side='right'caption='[[1ugo]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1ugo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UGO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1ugo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UGO FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">FANTOM 2 cDNA 4930405J06 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ugo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugo OCA], [http://pdbe.org/1ugo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ugo RCSB], [http://www.ebi.ac.uk/pdbsum/1ugo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ugo ProSAT], [http://www.topsan.org/Proteins/RSGI/1ugo TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ugo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ugo OCA], [https://pdbe.org/1ugo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ugo RCSB], [https://www.ebi.ac.uk/pdbsum/1ugo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ugo ProSAT], [https://www.topsan.org/Proteins/RSGI/1ugo TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAG5_MOUSE BAG5_MOUSE]] May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity).
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[https://www.uniprot.org/uniprot/BAG5_MOUSE BAG5_MOUSE] May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[BAG protein|BAG protein]]
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*[[BAG family proteins 3D structures|BAG family proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Aoki, M]]
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[[Category: Mus musculus]]
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[[Category: Arakawa, T]]
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[[Category: Aoki M]]
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[[Category: Carninci, P]]
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[[Category: Arakawa T]]
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[[Category: Endoh, H]]
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[[Category: Carninci P]]
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[[Category: Hayashi, F]]
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[[Category: Endoh H]]
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[[Category: Hayashizaki, Y]]
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[[Category: Hayashi F]]
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[[Category: Hirota, H]]
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[[Category: Hayashizaki Y]]
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[[Category: Inoue, M]]
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[[Category: Hirota H]]
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[[Category: Kawai, J]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kawai J]]
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[[Category: Matsuda, T]]
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[[Category: Kigawa T]]
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[[Category: Osanai, T]]
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[[Category: Matsuda T]]
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[[Category: Structural genomic]]
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[[Category: Osanai T]]
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[[Category: Seimiya, K]]
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[[Category: Seimiya K]]
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[[Category: Seki, E]]
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[[Category: Seki E]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Tanaka, A]]
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[[Category: Tanaka A]]
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[[Category: Terada, T]]
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[[Category: Terada T]]
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[[Category: Yabuki, T]]
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[[Category: Yabuki T]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Yoshida, M]]
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[[Category: Yoshida M]]
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[[Category: Chaperone]]
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[[Category: Rsgi]]
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[[Category: Triple helix bundle]]
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Current revision

Solution structure of the first Murine BAG domain of Bcl2-associated athanogene 5

PDB ID 1ugo

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