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1uit

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(New page: 200px<br /> <applet load="1uit" size="450" color="white" frame="true" align="right" spinBox="true" caption="1uit" /> '''Solution structure of RSGI RUH-006, The thi...)
Current revision (23:54, 27 December 2023) (edit) (undo)
 
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[[Image:1uit.gif|left|200px]]<br />
 
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<applet load="1uit" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1uit" />
 
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'''Solution structure of RSGI RUH-006, The third PDZ domain OF hDlg5 (KIAA0583) protein [Homo sapiens]'''<br />
 
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==Disease==
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==Solution structure of RSGI RUH-006, The third PDZ domain OF hDlg5 (KIAA0583) protein [Homo sapiens]==
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Known diseases associated with this structure: Crohn disease, susceptibility to OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=604090 604090]]
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<StructureSection load='1uit' size='340' side='right'caption='[[1uit]]' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[1uit]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UIT FirstGlance]. <br>
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1UIT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1UIT OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uit OCA], [https://pdbe.org/1uit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uit RCSB], [https://www.ebi.ac.uk/pdbsum/1uit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uit ProSAT], [https://www.topsan.org/Proteins/RSGI/1uit TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DLG5_HUMAN DLG5_HUMAN] May play a role at the plasma membrane in the maintenance of the structure of epithelial cells and in the transmission of extracellular signals to the membrane and cytoskeleton.<ref>PMID:11876824</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ui/1uit_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1uit ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Abe, T.]]
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[[Category: Abe T]]
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[[Category: Hayashi, F.]]
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[[Category: Hayashi F]]
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[[Category: Hirota, H.]]
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[[Category: Hirota H]]
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[[Category: Kobayashi, N.]]
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[[Category: Kobayashi N]]
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[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: hdlg5]]
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[[Category: maguk family]]
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[[Category: pdz domain]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomics]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 19:35:23 2007''
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Current revision

Solution structure of RSGI RUH-006, The third PDZ domain OF hDlg5 (KIAA0583) protein [Homo sapiens]

PDB ID 1uit

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