1v3y
From Proteopedia
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- | {{Seed}} | ||
- | [[Image:1v3y.png|left|200px]] | ||
- | + | ==The crystal structure of peptide deformylase from Thermus thermophilus HB8== | |
- | + | <StructureSection load='1v3y' size='340' side='right'caption='[[1v3y]], [[Resolution|resolution]] 1.81Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[1v3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V3Y FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.81Å</td></tr> | |
- | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OCS:CYSTEINESULFONIC+ACID'>OCS</scene></td></tr> | |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v3y OCA], [https://pdbe.org/1v3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v3y RCSB], [https://www.ebi.ac.uk/pdbsum/1v3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v3y ProSAT], [https://www.topsan.org/Proteins/RSGI/1v3y TOPSAN]</span></td></tr> | |
- | + | </table> | |
- | + | == Function == | |
- | + | [https://www.uniprot.org/uniprot/DEF_THETH DEF_THETH] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity). | |
- | + | == Evolutionary Conservation == | |
- | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
- | + | Check<jmol> | |
- | [[ | + | <jmolCheckbox> |
- | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v3/1v3y_consurf.spt"</scriptWhenChecked> |
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v3y ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
+ | __TOC__ | ||
+ | </StructureSection> | ||
+ | [[Category: Large Structures]] | ||
[[Category: Thermus thermophilus]] | [[Category: Thermus thermophilus]] | ||
- | [[Category: Ito | + | [[Category: Ito K]] |
- | [[Category: Kamo | + | [[Category: Kamo M]] |
- | [[Category: Kudo | + | [[Category: Kudo N]] |
- | [[Category: Lee | + | [[Category: Lee WC]] |
- | [[Category: Motoshim | + | [[Category: Motoshim H]] |
- | + | [[Category: Tanokura M]] | |
- | [[Category: Tanokura | + | |
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Current revision
The crystal structure of peptide deformylase from Thermus thermophilus HB8
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Categories: Large Structures | Thermus thermophilus | Ito K | Kamo M | Kudo N | Lee WC | Motoshim H | Tanokura M