1v5o

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[[Image:1v5o.jpg|left|200px]]
 
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{{Structure
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==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein==
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|PDB= 1v5o |SIZE=350|CAPTION= <scene name='initialview01'>1v5o</scene>
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<StructureSection load='1v5o' size='340' side='right'caption='[[1v5o]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1v5o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5O FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= RIKEN cDNA 1700011N24 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5o OCA], [https://pdbe.org/1v5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5o RCSB], [https://www.ebi.ac.uk/pdbsum/1v5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5o ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5o TOPSAN]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5o OCA], [http://www.ebi.ac.uk/pdbsum/1v5o PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v5o RCSB]</span>
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[https://www.uniprot.org/uniprot/DDI1_MOUSE DDI1_MOUSE] Probable aspartic protease (By similarity). Seems to act as a proteasomal shuttle which links the proteasome and replication fork proteins like RTF2. Required, with DDI2, for cellular survival following replication stress. Together or redudantly with DDI2, removes RTF2 from stalled forks to allow cell cycle progression after replication stress and maintains genome integrity (By similarity).[UniProtKB:I7HUG0][UniProtKB:Q8WTU0]
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5o_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1V5O is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5O OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5o ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Inoue M]]
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[[Category: Inoue, M.]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T.]]
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[[Category: Koshiba S]]
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[[Category: Koshiba, S.]]
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[[Category: Tomizawa T]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Tomizawa, T.]]
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[[Category: Zhao C]]
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[[Category: Yokoyama, S.]]
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[[Category: Zhao, C.]]
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[[Category: hypothetical protein]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: ubiquitin-like fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:19:55 2008''
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Current revision

Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 1700011N24Rik Protein

PDB ID 1v5o

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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