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1v5p
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==Solution Structure of the N-terminal Pleckstrin Homology Domain Of TAPP2 from Mouse== | ==Solution Structure of the N-terminal Pleckstrin Homology Domain Of TAPP2 from Mouse== | ||
| - | <StructureSection load='1v5p' size='340' side='right' caption='[[1v5p | + | <StructureSection load='1v5p' size='340' side='right'caption='[[1v5p]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1v5p]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1v5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5P FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5p OCA], [https://pdbe.org/1v5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5p RCSB], [https://www.ebi.ac.uk/pdbsum/1v5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5p ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5p TOPSAN]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PKHA2_MOUSE PKHA2_MOUSE] Binds specifically to phosphatidylinositol 3,4-diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane.<ref>PMID:12101241</ref> <ref>PMID:14516276</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5p ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5p ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hayashi | + | [[Category: Mus musculus]] |
| - | [[Category: Inoue | + | [[Category: Hayashi F]] |
| - | [[Category: Kigawa | + | [[Category: Inoue M]] |
| - | [[Category: Koshiba | + | [[Category: Kigawa T]] |
| - | [[Category: Li | + | [[Category: Koshiba S]] |
| - | + | [[Category: Li H]] | |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
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Current revision
Solution Structure of the N-terminal Pleckstrin Homology Domain Of TAPP2 from Mouse
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Categories: Large Structures | Mus musculus | Hayashi F | Inoue M | Kigawa T | Koshiba S | Li H | Yokoyama S
