1v5t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (23:58, 27 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein==
==Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein==
-
<StructureSection load='1v5t' size='340' side='right' caption='[[1v5t]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='1v5t' size='340' side='right'caption='[[1v5t]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1v5t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V5T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1v5t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5T FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 8430435I17 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5t OCA], [http://pdbe.org/1v5t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v5t RCSB], [http://www.ebi.ac.uk/pdbsum/1v5t PDBsum], [http://www.topsan.org/Proteins/RSGI/1v5t TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5t OCA], [https://pdbe.org/1v5t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5t RCSB], [https://www.ebi.ac.uk/pdbsum/1v5t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5t ProSAT], [https://www.topsan.org/Proteins/RSGI/1v5t TOPSAN]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/UBCP1_MOUSE UBCP1_MOUSE] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. Recruited to the 19S regulatory particle of the 26S proteasome through its interaction with 19S component PSMD2/RPN1. Once recruited, dephosphorylates 19S component PSMC2/RPT1 which impairs PSMC2 ATPase activity and disrupts 26S proteasome assembly. Has also been reported to stimulate the proteolytic activity of the 26S proteasome.[UniProtKB:Q8WVY7]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5t_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5t_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 18: Line 21:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Large Structures]]
-
[[Category: Inoue, M]]
+
[[Category: Mus musculus]]
-
[[Category: Kigawa, T]]
+
[[Category: Inoue M]]
-
[[Category: Koshiba, S]]
+
[[Category: Kigawa T]]
-
[[Category: Structural genomic]]
+
[[Category: Koshiba S]]
-
[[Category: Tochio, N]]
+
[[Category: Tochio N]]
-
[[Category: Yokoyama, S]]
+
[[Category: Yokoyama S]]
-
[[Category: Zhao, C]]
+
[[Category: Zhao C]]
-
[[Category: Hypothetical protein]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Ubiquitin-like fold]]
+
-
[[Category: Unknown function]]
+

Current revision

Solution Structure of the Ubiquitin-like Domain from Mouse Hypothetical 8430435I17Rik Protein

PDB ID 1v5t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1v5t"
Personal tools