1v5y

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[[Image:1v5y.gif|left|200px]]
 
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==Binding of coumarins to NAD(P)H:FMN oxidoreductase==
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The line below this paragraph, containing "STRUCTURE_1v5y", creates the "Structure Box" on the page.
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<StructureSection load='1v5y' size='340' side='right'caption='[[1v5y]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1v5y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri Aliivibrio fischeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V5Y FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4HC:4-HYDROXY-2H-CHROMEN-2-ONE'>4HC</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
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{{STRUCTURE_1v5y| PDB=1v5y | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v5y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v5y OCA], [https://pdbe.org/1v5y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v5y RCSB], [https://www.ebi.ac.uk/pdbsum/1v5y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v5y ProSAT]</span></td></tr>
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</table>
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'''Binding of coumarins to NAD(P)H:FMN oxidoreductase'''
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== Function ==
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[https://www.uniprot.org/uniprot/FRA1_ALIFS FRA1_ALIFS] Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective.
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== Evolutionary Conservation ==
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==About this Structure==
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[[Image:Consurf_key_small.gif|200px|right]]
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1V5Y is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Aliivibrio_fischeri Aliivibrio fischeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V5Y OCA].
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v5/1v5y_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v5y ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Aliivibrio fischeri]]
[[Category: Aliivibrio fischeri]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kobori, T.]]
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[[Category: Kobori T]]
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[[Category: Koike, H.]]
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[[Category: Koike H]]
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[[Category: Saigo, K.]]
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[[Category: Saigo K]]
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[[Category: Sasaki, H.]]
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[[Category: Sasaki H]]
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[[Category: Tanokura, M.]]
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[[Category: Tanokura M]]
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[[Category: Zenno, S.]]
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[[Category: Zenno S]]
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[[Category: Coumarin]]
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[[Category: Fmn oxidoreductase]]
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[[Category: Inhibitor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 12:07:38 2008''
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Current revision

Binding of coumarins to NAD(P)H:FMN oxidoreductase

PDB ID 1v5y

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