1v6e

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[[Image:1v6e.jpg|left|200px]]
 
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{{Structure
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==Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B==
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|PDB= 1v6e |SIZE=350|CAPTION= <scene name='initialview01'>1v6e</scene>
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<StructureSection load='1v6e' size='340' side='right'caption='[[1v6e]]' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1v6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V6E FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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|GENE= RIKEN cDNA 2410007D12 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v6e OCA], [https://pdbe.org/1v6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v6e RCSB], [https://www.ebi.ac.uk/pdbsum/1v6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v6e ProSAT], [https://www.topsan.org/Proteins/RSGI/1v6e TOPSAN]</span></td></tr>
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|DOMAIN=
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</table>
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|RELATEDENTRY=
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== Function ==
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v6e OCA], [http://www.ebi.ac.uk/pdbsum/1v6e PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1v6e RCSB]</span>
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[https://www.uniprot.org/uniprot/TBCB_MOUSE TBCB_MOUSE] Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.<ref>PMID:17184771</ref> <ref>PMID:17217416</ref>
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}}
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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'''Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B'''
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v6/1v6e_consurf.spt"</scriptWhenChecked>
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==About this Structure==
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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1V6E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA].
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v6e ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Inoue M]]
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[[Category: Inoue, M.]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T.]]
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[[Category: Koshiba S]]
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[[Category: Koshiba, S.]]
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[[Category: Saito K]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Saito, K.]]
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[[Category: Zhao C]]
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[[Category: Yokoyama, S.]]
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[[Category: Zhao, C.]]
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[[Category: cytoskeleton]]
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[[Category: cytoskeleton-associated protein ckap1]]
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[[Category: microtubule]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: structural genomic]]
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[[Category: tubulin folding cofactor b]]
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[[Category: tubulin-specific chaperone b]]
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[[Category: ubiquitin-like fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:20:03 2008''
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Current revision

Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B

PDB ID 1v6e

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