1v6e

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{{Seed}}
 
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[[Image:1v6e.png|left|200px]]
 
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==Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B==
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The line below this paragraph, containing "STRUCTURE_1v6e", creates the "Structure Box" on the page.
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<StructureSection load='1v6e' size='340' side='right'caption='[[1v6e]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1v6e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V6E FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v6e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v6e OCA], [https://pdbe.org/1v6e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v6e RCSB], [https://www.ebi.ac.uk/pdbsum/1v6e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v6e ProSAT], [https://www.topsan.org/Proteins/RSGI/1v6e TOPSAN]</span></td></tr>
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{{STRUCTURE_1v6e| PDB=1v6e | SCENE= }}
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</table>
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== Function ==
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===Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B===
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[https://www.uniprot.org/uniprot/TBCB_MOUSE TBCB_MOUSE] Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.<ref>PMID:17184771</ref> <ref>PMID:17217416</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1V6E is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V6E OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v6/1v6e_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v6e ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Inoue, M.]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Saito K]]
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[[Category: Saito, K.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Zhao C]]
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[[Category: Zhao, C.]]
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[[Category: Cytoskeleton]]
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[[Category: Cytoskeleton-associated protein ckap1]]
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[[Category: Microtubule]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Structural genomic]]
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[[Category: Tubulin folding cofactor b]]
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[[Category: Tubulin-specific chaperone b]]
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[[Category: Ubiquitin-like fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 18:08:32 2008''
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Current revision

Solution Structure of a N-terminal Ubiquitin-like Domain in Mouse Tubulin-specific Chaperone B

PDB ID 1v6e

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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