1v87

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (23:59, 27 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==Solution Structure of the Ring-H2 Finger Domain of Mouse Deltex Protein 2==
==Solution Structure of the Ring-H2 Finger Domain of Mouse Deltex Protein 2==
-
<StructureSection load='1v87' size='340' side='right' caption='[[1v87]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='1v87' size='340' side='right'caption='[[1v87]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1v87]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V87 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1V87 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1v87]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V87 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">RIKEN cDNA 2610524D08 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1v87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v87 OCA], [http://pdbe.org/1v87 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1v87 RCSB], [http://www.ebi.ac.uk/pdbsum/1v87 PDBsum], [http://www.topsan.org/Proteins/RSGI/1v87 TOPSAN]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v87 OCA], [https://pdbe.org/1v87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v87 RCSB], [https://www.ebi.ac.uk/pdbsum/1v87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v87 ProSAT], [https://www.topsan.org/Proteins/RSGI/1v87 TOPSAN]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE]] Recurrent site of retroviral integration in murine B-cell lymphomas.
+
[https://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE] Recurrent site of retroviral integration in murine B-cell lymphomas.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE]] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity).
+
[https://www.uniprot.org/uniprot/DTX2_MOUSE DTX2_MOUSE] Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/1v87_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/1v87_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
Line 23: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Large Structures]]
-
[[Category: Inoue, M]]
+
[[Category: Mus musculus]]
-
[[Category: Kigawa, T]]
+
[[Category: Inoue M]]
-
[[Category: Koshiba, S]]
+
[[Category: Kigawa T]]
-
[[Category: Miyamoto, K]]
+
[[Category: Koshiba S]]
-
[[Category: Muto, Y]]
+
[[Category: Miyamoto K]]
-
[[Category: Structural genomic]]
+
[[Category: Muto Y]]
-
[[Category: Tochio, N]]
+
[[Category: Tochio N]]
-
[[Category: Yokoyama, S]]
+
[[Category: Yokoyama S]]
-
[[Category: Metal binding protein]]
+
-
[[Category: Notch signaling]]
+
-
[[Category: Ring-h2 domain]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Zinc-binding domain]]
+

Current revision

Solution Structure of the Ring-H2 Finger Domain of Mouse Deltex Protein 2

PDB ID 1v87

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1v87"
Personal tools