This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
1v90
From Proteopedia
(Difference between revisions)
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| + | |||
==Solution structure by NMR means of delta-paluIT1-NH2== | ==Solution structure by NMR means of delta-paluIT1-NH2== | ||
| - | <StructureSection load='1v90' size='340' side='right' caption='[[1v90 | + | <StructureSection load='1v90' size='340' side='right'caption='[[1v90]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1v90]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1v90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pireneitega_luctuosa Pireneitega luctuosa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V90 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v90 OCA], [https://pdbe.org/1v90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v90 RCSB], [https://www.ebi.ac.uk/pdbsum/1v90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v90 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/T3D1A_PIRLC T3D1A_PIRLC] Binds at site 4 of sodium channels (Nav) and inhibits the fast inactivation of cockroach channels. This toxin is active only on insects. Has a potent activity against S.litura larvae.<ref>PMID:10971590</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v90_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v9/1v90_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v90 ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
| Line 27: | Line 28: | ||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 1v90" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Bosmans | + | [[Category: Pireneitega luctuosa]] |
| - | [[Category: Chagot | + | [[Category: Bosmans F]] |
| - | [[Category: Corzo | + | [[Category: Chagot B]] |
| - | [[Category: Darbon | + | [[Category: Corzo G]] |
| - | [[Category: Ferrat | + | [[Category: Darbon H]] |
| - | [[Category: Nakajima | + | [[Category: Ferrat G]] |
| - | [[Category: Pimentel | + | [[Category: Nakajima T]] |
| - | [[Category: Tytgat | + | [[Category: Pimentel C]] |
| - | + | [[Category: Tytgat J]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Solution structure by NMR means of delta-paluIT1-NH2
| |||||||||||
Categories: Large Structures | Pireneitega luctuosa | Bosmans F | Chagot B | Corzo G | Darbon H | Ferrat G | Nakajima T | Pimentel C | Tytgat J
