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1vbj
From Proteopedia
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==The crystal structure of prostaglandin F synthase from Trypanosoma brucei== | ==The crystal structure of prostaglandin F synthase from Trypanosoma brucei== | ||
| - | <StructureSection load='1vbj' size='340' side='right' caption='[[1vbj]], [[Resolution|resolution]] 2.10Å' scene=''> | + | <StructureSection load='1vbj' size='340' side='right'caption='[[1vbj]], [[Resolution|resolution]] 2.10Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1vbj]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1vbj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VBJ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vbj OCA], [https://pdbe.org/1vbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vbj RCSB], [https://www.ebi.ac.uk/pdbsum/1vbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vbj ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PGFS_TRYBB PGFS_TRYBB] Catalyzes the NADP-dependent formation of prostaglandin F2-alpha from prostaglandin H2. Has also aldo/ketoreductase activity towards the synthetic substrates 9,10-phenanthrenequinone and p-nitrobenzaldehyde.<ref>PMID:11067881</ref> |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
| - | *[[Prostaglandin F synthase|Prostaglandin F synthase]] | + | *[[Prostaglandin F synthase 3D structures|Prostaglandin F synthase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Trypanosoma brucei]] |
| - | [[Category: | + | [[Category: Inoue T]] |
| - | + | ||
Current revision
The crystal structure of prostaglandin F synthase from Trypanosoma brucei
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