1vcs

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:01, 28 December 2023) (edit) (undo)
 
(13 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1vcs.gif|left|200px]]
 
-
{{Structure
+
==Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]==
-
|PDB= 1vcs |SIZE=350|CAPTION= <scene name='initialview01'>1vcs</scene>
+
<StructureSection load='1vcs' size='340' side='right'caption='[[1vcs]]' scene=''>
-
|SITE=
+
== Structural highlights ==
-
|LIGAND=
+
<table><tr><td colspan='2'>[[1vcs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCS FirstGlance]. <br>
-
|ACTIVITY=
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
|GENE= Mus musculus adult male lung cDNA, RIKEN full-length enriched library, clone:1200014A22 product: Vti1a (amino acid 6-94) ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcs OCA], [https://pdbe.org/1vcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcs RCSB], [https://www.ebi.ac.uk/pdbsum/1vcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcs ProSAT], [https://www.topsan.org/Proteins/RSGI/1vcs TOPSAN]</span></td></tr>
-
}}
+
</table>
-
 
+
== Function ==
-
'''Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]'''
+
[https://www.uniprot.org/uniprot/VTI1A_MOUSE VTI1A_MOUSE] V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence.<ref>PMID:19138172</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
==About this Structure==
+
Check<jmol>
-
1VCS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA].
+
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcs_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vcs ConSurf].
 +
<div style="clear:both"></div>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Single protein]]
+
[[Category: Abe T]]
-
[[Category: Abe, T.]]
+
[[Category: Hirota H]]
-
[[Category: Hirota, H.]]
+
[[Category: Kigawa T]]
-
[[Category: Kigawa, T.]]
+
[[Category: Koshiba S]]
-
[[Category: Koshiba, S.]]
+
[[Category: Tomizawa T]]
-
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
+
[[Category: Yokoyama S]]
-
[[Category: Tomizawa, T.]]
+
-
[[Category: Yokoyama, S.]]
+
-
[[Category: habc domain]]
+
-
[[Category: left-handed twist]]
+
-
[[Category: membrane fusion]]
+
-
[[Category: riken structural genomics/proteomics initiative]]
+
-
[[Category: rsgi]]
+
-
[[Category: snare]]
+
-
[[Category: structural genomic]]
+
-
[[Category: up and down three helix bundle]]
+
-
[[Category: vesicle transport]]
+
-
[[Category: vti1]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:43:49 2008''
+

Current revision

Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]

PDB ID 1vcs

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1vcs"
Personal tools