1vcs

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{{Seed}}
 
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[[Image:1vcs.png|left|200px]]
 
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==Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]==
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The line below this paragraph, containing "STRUCTURE_1vcs", creates the "Structure Box" on the page.
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<StructureSection load='1vcs' size='340' side='right'caption='[[1vcs]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1vcs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCS FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcs OCA], [https://pdbe.org/1vcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcs RCSB], [https://www.ebi.ac.uk/pdbsum/1vcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcs ProSAT], [https://www.topsan.org/Proteins/RSGI/1vcs TOPSAN]</span></td></tr>
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{{STRUCTURE_1vcs| PDB=1vcs | SCENE= }}
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</table>
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== Function ==
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===Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]===
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[https://www.uniprot.org/uniprot/VTI1A_MOUSE VTI1A_MOUSE] V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence.<ref>PMID:19138172</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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1VCS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vcs ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Abe, T.]]
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[[Category: Abe T]]
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[[Category: Hirota, H.]]
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[[Category: Hirota H]]
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[[Category: Kigawa, T.]]
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[[Category: Kigawa T]]
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[[Category: Koshiba, S.]]
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[[Category: Koshiba S]]
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[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
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[[Category: Tomizawa T]]
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[[Category: Tomizawa, T.]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S.]]
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[[Category: Habc domain]]
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[[Category: Left-handed twist]]
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[[Category: Membrane fusion]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: Rsgi]]
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[[Category: Snare]]
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[[Category: Structural genomic]]
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[[Category: Up and down three helix bundle]]
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[[Category: Vesicle transport]]
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[[Category: Vti1]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 11:50:25 2008''
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Current revision

Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]

PDB ID 1vcs

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