1vcs

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(New page: 200px<br /><applet load="1vcs" size="450" color="white" frame="true" align="right" spinBox="true" caption="1vcs" /> '''Solution Structure of RSGI RUH-009, an N-Ter...)
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[[Image:1vcs.gif|left|200px]]<br /><applet load="1vcs" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1vcs" />
 
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'''Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]'''<br />
 
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==About this Structure==
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==Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]==
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1VCS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA].
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<StructureSection load='1vcs' size='340' side='right'caption='[[1vcs]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1vcs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VCS FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vcs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vcs OCA], [https://pdbe.org/1vcs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vcs RCSB], [https://www.ebi.ac.uk/pdbsum/1vcs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vcs ProSAT], [https://www.topsan.org/Proteins/RSGI/1vcs TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VTI1A_MOUSE VTI1A_MOUSE] V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non-conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be concerned with increased secretion of cytokines associated with cellular senescence.<ref>PMID:19138172</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vc/1vcs_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vcs ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: Single protein]]
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[[Category: Abe T]]
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[[Category: Abe, T.]]
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[[Category: Hirota H]]
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[[Category: Hirota, H.]]
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[[Category: Kigawa T]]
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[[Category: Kigawa, T.]]
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[[Category: Koshiba S]]
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[[Category: Koshiba, S.]]
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[[Category: Tomizawa T]]
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[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
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[[Category: Yokoyama S]]
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[[Category: Tomizawa, T.]]
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[[Category: Yokoyama, S.]]
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[[Category: habc domain]]
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[[Category: left-handed twist]]
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[[Category: membrane fusion]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: snare]]
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[[Category: structural genomics]]
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[[Category: up and down three helix bundle]]
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[[Category: vesicle transport]]
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[[Category: vti1]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 04:35:36 2007''
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Current revision

Solution Structure of RSGI RUH-009, an N-Terminal Domain of Vti1a [Mus musculus]

PDB ID 1vcs

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