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2o5g

From Proteopedia

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[[Image:2o5g.jpg|left|200px]]
 
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{{Structure
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==Calmodulin-smooth muscle light chain kinase peptide complex==
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|PDB= 2o5g |SIZE=350|CAPTION= <scene name='initialview01'>2o5g</scene>, resolution 1.08&Aring;
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<StructureSection load='2o5g' size='340' side='right'caption='[[2o5g]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene> and <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
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<table><tr><td colspan='2'>[[2o5g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O5G FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
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|GENE= CALM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9031 Gallus gallus])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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}}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o5g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o5g OCA], [https://pdbe.org/2o5g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o5g RCSB], [https://www.ebi.ac.uk/pdbsum/2o5g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o5g ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CALM_CHICK CALM_CHICK] Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o5/2o5g_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o5g ConSurf].
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<div style="clear:both"></div>
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'''Calmodulin-smooth muscle light chain kinase peptide complex'''
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==See Also==
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*[[Calmodulin 3D structures|Calmodulin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2O5G is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O5G OCA].
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
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[[Category: Protein complex]]
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[[Category: Large Structures]]
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[[Category: Alber, T.]]
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[[Category: Alber T]]
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[[Category: Frederick, K K.]]
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[[Category: Frederick KK]]
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[[Category: Kranz, J K.]]
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[[Category: Kranz JK]]
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[[Category: Ng, H L.]]
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[[Category: Ng HL]]
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[[Category: Schneeweis, J K.]]
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[[Category: Schneeweis JK]]
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[[Category: Valentine, K G.]]
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[[Category: Valentine KG]]
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[[Category: Wand, A J.]]
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[[Category: Wand AJ]]
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[[Category: ACE]]
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[[Category: CA]]
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[[Category: NH2]]
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[[Category: SO4]]
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[[Category: metal binding protein]]
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[[Category: protein-peptide complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:55:22 2008''
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Current revision

Calmodulin-smooth muscle light chain kinase peptide complex

PDB ID 2o5g

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