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2o8p

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==Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470==
==Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470==
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<StructureSection load='2o8p' size='340' side='right' caption='[[2o8p]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
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<StructureSection load='2o8p' size='340' side='right'caption='[[2o8p]], [[Resolution|resolution]] 1.82&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2o8p]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8P OCA]. <br>
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<table><tr><td colspan='2'>[[2o8p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Cryptosporidium_parvum Cryptosporidium parvum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O8P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2O8P FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2o8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o8p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2o8p RCSB], [http://www.ebi.ac.uk/pdbsum/2o8p PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2o8p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2o8p OCA], [https://pdbe.org/2o8p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2o8p RCSB], [https://www.ebi.ac.uk/pdbsum/2o8p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2o8p ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q5CYG0_CRYPI Q5CYG0_CRYPI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o8/2o8p_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o8/2o8p_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2o8p ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Characterization of 14-3-3 proteins from Cryptosporidium parvum.,Brokx SJ, Wernimont AK, Dong A, Wasney GA, Lin YH, Lew J, Vedadi M, Lee WH, Hui R PLoS One. 2011;6(8):e14827. Epub 2011 Aug 11. PMID:21853016<ref>PMID:21853016</ref>
Characterization of 14-3-3 proteins from Cryptosporidium parvum.,Brokx SJ, Wernimont AK, Dong A, Wasney GA, Lin YH, Lew J, Vedadi M, Lee WH, Hui R PLoS One. 2011;6(8):e14827. Epub 2011 Aug 11. PMID:21853016<ref>PMID:21853016</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2o8p" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Cryptosporidium parvum]]
[[Category: Cryptosporidium parvum]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bochkarev, A.]]
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[[Category: Arrowsmith CH]]
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[[Category: Brokx, S J.]]
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[[Category: Bochkarev A]]
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[[Category: Dong, A.]]
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[[Category: Brokx SJ]]
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[[Category: Edwards, A M.]]
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[[Category: Dong A]]
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[[Category: Hassanali, A.]]
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[[Category: Edwards AM]]
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[[Category: Hui, R.]]
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[[Category: Hassanali A]]
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[[Category: Kozieradzki, I.]]
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[[Category: Hui R]]
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[[Category: Lew, J.]]
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[[Category: Kozieradzki I]]
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[[Category: Lin, L.]]
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[[Category: Lew J]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Lin L]]
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[[Category: Sundstrom, M.]]
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[[Category: Sundstrom M]]
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[[Category: Vedadi, M.]]
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[[Category: Vedadi M]]
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[[Category: Walker, J R.]]
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[[Category: Walker JR]]
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[[Category: Wasney, G.]]
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[[Category: Wasney G]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]
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[[Category: Zhao, Y.]]
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[[Category: Zhao Y]]
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[[Category: 14-3-3]]
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[[Category: Cell regulator protein]]
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[[Category: Cryptosporidium parvum]]
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[[Category: Sgc]]
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[[Category: Signaling protein]]
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[[Category: Structural genomic]]
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[[Category: Structural genomics consortium]]
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Current revision

Crystal structure of a putative 14-3-3 protein from Cryptosporidium parvum, cgd7_2470

PDB ID 2o8p

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