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2ofi

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==Crystal Structure of 3-methyladenine DNA Glycosylase I (TAG) bound to DNA/3mA==
==Crystal Structure of 3-methyladenine DNA Glycosylase I (TAG) bound to DNA/3mA==
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<StructureSection load='2ofi' size='340' side='right' caption='[[2ofi]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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<StructureSection load='2ofi' size='340' side='right'caption='[[2ofi]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ofi]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2OFI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ofi]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OFI FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=ADK:3-METHYL-3H-PURIN-6-YLAMINE'>ADK</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ofi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofi OCA], [http://pdbe.org/2ofi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2ofi RCSB], [http://www.ebi.ac.uk/pdbsum/2ofi PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ofi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofi OCA], [https://pdbe.org/2ofi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ofi RCSB], [https://www.ebi.ac.uk/pdbsum/2ofi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ofi ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8Z2A5_SALTI Q8Z2A5_SALTI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/2ofi_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/of/2ofi_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[DNA glycosylase|DNA glycosylase]]
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*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Eichman, B F]]
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[[Category: Large Structures]]
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[[Category: Hollis, T]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhi]]
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[[Category: Metz, A H]]
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[[Category: Eichman BF]]
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[[Category: 3-methyladenine]]
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[[Category: Hollis T]]
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[[Category: 3-methyladenine dna glycosylase i-dna complex]]
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[[Category: Metz AH]]
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[[Category: Base excision]]
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[[Category: Dna repair]]
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[[Category: Glycosylase]]
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[[Category: Helix-hairpin-helix]]
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Current revision

Crystal Structure of 3-methyladenine DNA Glycosylase I (TAG) bound to DNA/3mA

PDB ID 2ofi

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