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2oof
From Proteopedia
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| - | [[Image:2oof.gif|left|200px]] | ||
| - | + | ==The crystal structure of 4-imidazolone-5-propanoate amidohydrolase from environmental sample== | |
| - | + | <StructureSection load='2oof' size='340' side='right'caption='[[2oof]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2oof]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Unidentified Unidentified]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OOF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OOF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | | | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oof FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oof OCA], [https://pdbe.org/2oof PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oof RCSB], [https://www.ebi.ac.uk/pdbsum/2oof PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oof ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2oof TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | ''' | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/HUTI_AERHH HUTI_AERHH] Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.[HAMAP-Rule:MF_00372] | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oo/2oof_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| - | + | </jmolCheckbox> | |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oof ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | [ | + | __TOC__ |
| - | [[ | + | </StructureSection> |
| - | + | [[Category: Large Structures]] | |
| - | + | [[Category: Unidentified]] | |
| - | [[Category: | + | [[Category: Burley SK]] |
| - | [[Category: | + | [[Category: Eswaramoorthy S]] |
| - | [[Category: | + | [[Category: Swaminathan S]] |
| - | [[Category: | + | [[Category: Tyagi R]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
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Current revision
The crystal structure of 4-imidazolone-5-propanoate amidohydrolase from environmental sample
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