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2opj
From Proteopedia
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| - | {{Seed}} | ||
| - | [[Image:2opj.png|left|200px]] | ||
| - | + | ==Crystal structure of O-succinylbenzoate synthase== | |
| - | + | <StructureSection load='2opj' size='340' side='right'caption='[[2opj]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2opj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca_YX Thermobifida fusca YX]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OPJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OPJ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2opj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2opj OCA], [https://pdbe.org/2opj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2opj RCSB], [https://www.ebi.ac.uk/pdbsum/2opj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2opj ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2opj TOPSAN]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/MENC_THEFY MENC_THEFY] Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 2-succinylbenzoate (OSB) (PubMed:24060347, PubMed:24872444). Does not show N-succinylamino acid racemase (NSAR) activity with N-succinyl-L-phenylglycine as substrate (PubMed:24872444).<ref>PMID:24060347</ref> <ref>PMID:24872444</ref> | |
| - | + | == Evolutionary Conservation == | |
| - | == | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/2opj_consurf.spt"</scriptWhenChecked> |
| - | [[ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | [[ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[ | + | </jmolCheckbox> |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2opj ConSurf]. |
| - | [[ | + | <div style="clear:both"></div> |
| - | [ | + | == References == |
| - | [[ | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Thermobifida fusca YX]] |
| - | + | [[Category: Burley SK]] | |
| - | + | [[Category: Sugadev R]] | |
| + | [[Category: Swaminathan S]] | ||
Current revision
Crystal structure of O-succinylbenzoate synthase
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