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3ewb
From Proteopedia
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| - | [[Image:3ewb.png|left|200px]] | ||
| - | + | ==Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes== | |
| + | <StructureSection load='3ewb' size='340' side='right'caption='[[3ewb]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ewb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_serotype_4b_str._F2365 Listeria monocytogenes serotype 4b str. F2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewb OCA], [https://pdbe.org/3ewb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewb RCSB], [https://www.ebi.ac.uk/pdbsum/3ewb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewb ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ewb TOPSAN]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LEU1_LISMF LEU1_LISMF] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewb_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ewb ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | === | + | ==See Also== |
| - | + | *[[2-isopropylmalate synthase 3D structures|2-isopropylmalate synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | [[Category: | + | [[Category: Listeria monocytogenes serotype 4b str. F2365]] |
| - | [[Category: Listeria monocytogenes serotype 4b str. | + | [[Category: Almo SC]] |
| - | [[Category: Almo | + | [[Category: Burley SK]] |
| - | [[Category: Burley | + | [[Category: Gilmore M]] |
| - | [[Category: Gilmore | + | [[Category: Hu S]] |
| - | [[Category: Hu | + | [[Category: Maletic M]] |
| - | [[Category: Maletic | + | [[Category: Ramagopal UA]] |
| - | + | [[Category: Rodgers L]] | |
| - | [[Category: Ramagopal | + | [[Category: Toro R]] |
| - | [[Category: Rodgers | + | |
| - | [[Category: Toro | + | |
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Current revision
Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes
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