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3ewb

From Proteopedia

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{{Seed}}
 
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[[Image:3ewb.jpg|left|200px]]
 
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==Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes==
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The line below this paragraph, containing "STRUCTURE_3ewb", creates the "Structure Box" on the page.
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<StructureSection load='3ewb' size='340' side='right'caption='[[3ewb]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3ewb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_serotype_4b_str._F2365 Listeria monocytogenes serotype 4b str. F2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EWB FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3ewb| PDB=3ewb | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ewb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ewb OCA], [https://pdbe.org/3ewb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ewb RCSB], [https://www.ebi.ac.uk/pdbsum/3ewb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ewb ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3ewb TOPSAN]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LEU1_LISMF LEU1_LISMF] Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ew/3ewb_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ewb ConSurf].
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<div style="clear:both"></div>
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===Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes===
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==See Also==
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*[[2-isopropylmalate synthase 3D structures|2-isopropylmalate synthase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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3EWB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Listeria_monocytogenes_str._4b_f2365 Listeria monocytogenes str. 4b f2365]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EWB OCA].
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[[Category: Large Structures]]
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[[Category: 2-isopropylmalate synthase]]
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[[Category: Listeria monocytogenes serotype 4b str. F2365]]
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[[Category: Listeria monocytogenes str. 4b f2365]]
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[[Category: Almo SC]]
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[[Category: Almo, S C.]]
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[[Category: Burley SK]]
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[[Category: Burley, S K.]]
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[[Category: Gilmore M]]
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[[Category: Gilmore, M.]]
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[[Category: Hu S]]
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[[Category: Hu, S.]]
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[[Category: Maletic M]]
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[[Category: Maletic, M.]]
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[[Category: Ramagopal UA]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics.]]
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[[Category: Rodgers L]]
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[[Category: Ramagopal, U A.]]
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[[Category: Toro R]]
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[[Category: Rodgers, L.]]
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[[Category: Toro, R.]]
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[[Category: Amino-acid biosynthesis]]
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[[Category: Branched-chain amino acid biosynthesis]]
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[[Category: Leua]]
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[[Category: Leucine biosynthesis]]
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[[Category: New york sgx research center for structural genomic]]
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[[Category: Nysgxrc]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Structural genomic]]
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[[Category: Transferase]]
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[[Category: Unknown function]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 24 11:34:24 2008''
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Current revision

Crystal structure of N-terminal domain of putative 2-isopropylmalate synthase from Listeria monocytogenes

PDB ID 3ewb

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