3f3y
From Proteopedia
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==Crystal structure of human cytosolic sulfotransferase SULT2A1 in complex with PAP and lithocholic acid== | ==Crystal structure of human cytosolic sulfotransferase SULT2A1 in complex with PAP and lithocholic acid== | ||
- | <StructureSection load='3f3y' size='340' side='right' caption='[[3f3y]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='3f3y' size='340' side='right'caption='[[3f3y]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3f3y]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3f3y]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F3Y FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4OA:(3BETA,5BETA,14BETA,17ALPHA)-3-HYDROXYCHOLAN-24-OIC+ACID'>4OA</scene>, <scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f3y OCA], [https://pdbe.org/3f3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f3y RCSB], [https://www.ebi.ac.uk/pdbsum/3f3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f3y ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/ST2A1_HUMAN ST2A1_HUMAN] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfonation of steroids and bile acids in the liver and adrenal glands. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
- | *[[Sulfotransferase|Sulfotransferase]] | + | *[[Sulfotransferase 3D structures|Sulfotransferase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Homo sapiens]] |
- | [[Category: | + | [[Category: Large Structures]] |
- | [[Category: Amaya | + | [[Category: Amaya M]] |
- | [[Category: Dong | + | [[Category: Dong A]] |
- | [[Category: Edwards | + | [[Category: Edwards AM]] |
- | [[Category: Pan | + | [[Category: Pan PW]] |
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Current revision
Crystal structure of human cytosolic sulfotransferase SULT2A1 in complex with PAP and lithocholic acid
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Categories: Homo sapiens | Large Structures | Amaya M | Dong A | Edwards AM | Pan PW