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3fcm

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==Crystal structure of a NUDIX hydrolase from Clostridium perfringens==
==Crystal structure of a NUDIX hydrolase from Clostridium perfringens==
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<StructureSection load='3fcm' size='340' side='right' caption='[[3fcm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='3fcm' size='340' side='right'caption='[[3fcm]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3fcm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Clop1 Clop1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3FCM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3fcm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_perfringens_ATCC_13124 Clostridium perfringens ATCC 13124]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FCM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FCM FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CPF_0662 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=195103 CLOP1])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fcm OCA], [https://pdbe.org/3fcm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fcm RCSB], [https://www.ebi.ac.uk/pdbsum/3fcm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fcm ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3fcm TOPSAN]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3fcm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fcm OCA], [http://pdbe.org/3fcm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3fcm RCSB], [http://www.ebi.ac.uk/pdbsum/3fcm PDBsum], [http://www.topsan.org/Proteins/NYSGXRC/3fcm TOPSAN]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0H2YP99_CLOP1 A0A0H2YP99_CLOP1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fcm_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fc/3fcm_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fcm ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fcm ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Clop1]]
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[[Category: Clostridium perfringens ATCC 13124]]
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[[Category: Burley, S K]]
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[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Burley SK]]
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[[Category: Palani, K]]
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[[Category: Palani K]]
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[[Category: Swaninathan, S]]
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[[Category: Swaninathan S]]
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[[Category: Hydrolase]]
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[[Category: Nudix]]
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[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
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Current revision

Crystal structure of a NUDIX hydrolase from Clostridium perfringens

PDB ID 3fcm

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