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3fdw
From Proteopedia
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==Crystal structure of a C2 domain from human synaptotagmin-like protein 4== | ==Crystal structure of a C2 domain from human synaptotagmin-like protein 4== | ||
| - | <StructureSection load='3fdw' size='340' side='right' caption='[[3fdw]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='3fdw' size='340' side='right'caption='[[3fdw]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3fdw]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3fdw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FDW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FDW FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fdw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fdw OCA], [https://pdbe.org/3fdw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fdw RCSB], [https://www.ebi.ac.uk/pdbsum/3fdw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fdw ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3fdw TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/SYTL4_HUMAN SYTL4_HUMAN] Modulates exocytosis of dense-core granules and secretion of hormones in the pancreas and the pituitary. Interacts with vesicles containing negatively charged phospholipids in a Ca(2+)-independent manner (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fdw_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fd/3fdw_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
| - | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fdw ConSurf]. |
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
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| + | ==See Also== | ||
| + | *[[Exophilin 3D structures|Exophilin 3D structures]] | ||
| + | *[[Synaptotagmin 3D structures|Synaptotagmin 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Almo SC]] |
| - | [[Category: | + | [[Category: Bain KT]] |
| - | [[Category: | + | [[Category: Bonanno JB]] |
| - | [[Category: | + | [[Category: Burley SK]] |
| - | [[Category: | + | [[Category: Miller S]] |
| - | [[Category: Romero | + | [[Category: Romero R]] |
| - | [[Category: Rutter | + | [[Category: Rutter M]] |
| - | [[Category: Sauder | + | [[Category: Sauder JM]] |
| - | [[Category: Wasserman | + | [[Category: Wasserman S]] |
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Current revision
Crystal structure of a C2 domain from human synaptotagmin-like protein 4
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Categories: Homo sapiens | Large Structures | Almo SC | Bain KT | Bonanno JB | Burley SK | Miller S | Romero R | Rutter M | Sauder JM | Wasserman S
