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3pjr
From Proteopedia
(Difference between revisions)
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==HELICASE SUBSTRATE COMPLEX== | ==HELICASE SUBSTRATE COMPLEX== | ||
| - | <StructureSection load='3pjr' size='340' side='right' caption='[[3pjr]], [[Resolution|resolution]] 3.30Å' scene=''> | + | <StructureSection load='3pjr' size='340' side='right'caption='[[3pjr]], [[Resolution|resolution]] 3.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3pjr]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3pjr]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PJR FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pjr OCA], [https://pdbe.org/3pjr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pjr RCSB], [https://www.ebi.ac.uk/pdbsum/3pjr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pjr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PCRA_GEOSE PCRA_GEOSE] DNA helicase. Has a broad nucleotide specificity, even being able to hydrolyze ethenonucleotides, and is able to couple the hydrolysis to unwinding of DNA substrates. It is a 3'-5' helicase but at high protein concentrations it can also displace a substrate with a 5' tail. Preferred substrate being one with both single and double-stranded regions of DNA. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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==See Also== | ==See Also== | ||
*[[Helicase|Helicase]] | *[[Helicase|Helicase]] | ||
| - | *[[ | + | *[[Helicase 3D structures|Helicase 3D structures]] |
| - | + | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Geobacillus stearothermophilus]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Dillingham MS]] |
| - | [[Category: | + | [[Category: Soultanas P]] |
| - | [[Category: | + | [[Category: Subramanya HS]] |
| - | [[Category: | + | [[Category: Velankar SS]] |
| - | [[Category: | + | [[Category: Wigley DB]] |
| - | + | ||
Current revision
HELICASE SUBSTRATE COMPLEX
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