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4p0e
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 4p0e is ON HOLD Authors: JImin, Z. Jin, J. Nan, W. Description: YhdE E33A (p21212121 space group)) |
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| - | '''Unreleased structure''' | ||
| - | + | ==YhdE E33A (p212121 space group)== | |
| - | + | <StructureSection load='4p0e' size='340' side='right'caption='[[4p0e]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4p0e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4P0E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4P0E FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4p0e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4p0e OCA], [https://pdbe.org/4p0e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4p0e RCSB], [https://www.ebi.ac.uk/pdbsum/4p0e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4p0e ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/NTPPA_ECOLI NTPPA_ECOLI] Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP (PubMed:24210219, PubMed:25658941, PubMed:28811554). Can also hydrolyze TTP and the modified nucleotides 5-methyl-UTP (m(5)UTP), pseudo-UTP and 5-methyl-CTP (m(5)CTP). Has weak activity with CTP (PubMed:24210219, PubMed:25658941). May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids (PubMed:24210219, PubMed:25658941). Important in maintenance of cell shape (PubMed:25658941).<ref>PMID:24210219</ref> <ref>PMID:25658941</ref> <ref>PMID:28811554</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli K-12]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Jia Z]] | ||
| + | [[Category: Jin J]] | ||
| + | [[Category: Wang N]] | ||
| + | [[Category: Zheng J]] | ||
Current revision
YhdE E33A (p212121 space group)
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