This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4pir

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:44, 28 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
 +
==X-ray structure of the mouse serotonin 5-HT3 receptor==
==X-ray structure of the mouse serotonin 5-HT3 receptor==
-
<StructureSection load='4pir' size='340' side='right' caption='[[4pir]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
+
<StructureSection load='4pir' size='340' side='right'caption='[[4pir]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4pir]] is a 10 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PIR FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4pir]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4PIR FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4pir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pir OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4pir RCSB], [http://www.ebi.ac.uk/pdbsum/4pir PDBsum]</span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4pir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4pir OCA], [https://pdbe.org/4pir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4pir RCSB], [https://www.ebi.ac.uk/pdbsum/4pir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4pir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE]] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
+
[https://www.uniprot.org/uniprot/5HT3A_MOUSE 5HT3A_MOUSE] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 16: Line 18:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 4pir" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[5-hydroxytryptamine receptor 3D structures|5-hydroxytryptamine receptor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Deluz, C]]
+
[[Category: Lama glama]]
-
[[Category: Desmyter, A]]
+
[[Category: Large Structures]]
-
[[Category: Graff, A]]
+
[[Category: Mus musculus]]
-
[[Category: Grasso, L]]
+
[[Category: Deluz C]]
-
[[Category: Hassaine, G]]
+
[[Category: Desmyter A]]
-
[[Category: Hovius, R]]
+
[[Category: Graff A]]
-
[[Category: Li, X D]]
+
[[Category: Grasso L]]
-
[[Category: Moreau, C]]
+
[[Category: Hassaine G]]
-
[[Category: Nury, H]]
+
[[Category: Hovius R]]
-
[[Category: Poitevin, F]]
+
[[Category: Li X-D]]
-
[[Category: Stahlberg, H]]
+
[[Category: Moreau C]]
-
[[Category: Tol, M B]]
+
[[Category: Nury H]]
-
[[Category: Tomizaki, T]]
+
[[Category: Poitevin F]]
-
[[Category: Vogel, H]]
+
[[Category: Stahlberg H]]
-
[[Category: Wyss, R]]
+
[[Category: Tol MB]]
-
[[Category: Ion channel]]
+
[[Category: Tomizaki T]]
-
[[Category: Membrane transport]]
+
[[Category: Vogel H]]
-
[[Category: Transport protein]]
+
[[Category: Wyss R]]

Current revision

X-ray structure of the mouse serotonin 5-HT3 receptor

PDB ID 4pir

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4pir"
Personal tools